2024-2025 M3/M4 Course Syllabi
Pathology & Laboratory Medicine
COURSE NUMBER:
15 01 21
TITLE:
NEUROPATHOLOGY
This rotation is designed to help the student become familiar with common pathologic processes that involve the central, peripheral nervous systems, nerve and muscle. The rotation (4 weeks only) includes participation in the preparation and interpretation of frozen sections/ intraoperative smear preparations, brain cutting, and histologic diagnosis of neurosurgical specimens; the importance of correlation with clinicoradiologic data is emphasized. Review of PowerPoints and glass slide study sets with attendings will put the material in clinical and practical context for students going into all specialties of medicine.
PREREQUISITES:
None
expand all

GENERAL INFORMATION

COURSE YEAR:
M4
CREDIT HOURS:
8
CREDIT WEEKS:
2
DOMESTIC VISITING:
NO
INTERNATIONAL VISITING:
NO
GRADED:
Honors/High Pass/Pass/Fail
COURSE QUALIFICATIONS:
STATUS:
Full-Time   
OFFERED AS FULL-TIME AND PART-TIME: NO
ALLOWS OVERLAP: YES
COURSE LENGTH:
2 wks
DIRECTOR:
Ady Kendler, MD, PHD
ady.kendler@uc.edu
513.584.3841
Lab Medicine UH, 110
Rachel Jug
jugrl@ucmail.uc.edu
513-584-7290
LMB, 4051
ADMINISTRATIVE SUPPORT PERSON:
Lindsay Stover
stoverlr@ucmail.uc.edu
513-584-1323
LMB, 4067
SITE(S):
Laboratory Medicine Building
MAX ENROLL:
1 
ROTATIONS:
Rotation Dates Max

NOTE: If a rotation is offered in both 2 and 4 week slots, the max capacity is limited to the actual spots offered for the 4 weeks. (ie: the 2 week rotations listed share the max of the 4 week rotation)
WORKING HOURS:
8:00 am - 5:00 pm; Monday - Friday
REPORT 1ST DAY:
Report to Laboratory Medicine Building, Suite 110, ask to meet with the Neuropathologist on Service (Dr. Kendler or Dr. Hagen); at 9am on the first day of the rotation. Please arrive on day one at 9:00. You are free to wear scrubs if you like. At some point, on your first day, please touch base with Dr. Kendler, kendlea@ucmail.uc.edu the faculty in charge of your rotation, so that they can go over specific expectations. To find the lab: If you walk into the front of the hospital, go to the big staircase on the right. Once you walk up to the top turn right and walk straight back passing elevators go until you reach a dead end and 2 doors on the right. That’s pathology. The second door on the right is open and once you get inside the front desk will guide you. Let me know if you need anything else.
COMMENTS:
On the Thursday of your last week, you will give a short (15-20 minute) case presentation as part of the SP Case Conference that week. I would recommend asking either the faculty in charge of your rotation or the attending faculty during your first week if they have an interesting case that you could present so that you have plenty of time to prepare. If the slides need to pulled, Alex or Vinay can assist you with requesting them. When you are ready, one of the residents will help you take pictures of the slides to use during your presentation. Students are expected to prepare two CPC-style PowerPoint presentations per week of the rotation (20 mins. each), and present them to the neuropathology division or at Pathology Residents 8 AM conferences.

INSTRUCTION

LEARNING ACTIVITIES:
  • Case-Based Instruction/Learning
  • Concept Mapping (allows learners to organize and represent knowledge in an explicit interconnected network)
  • Conference
  • Demonstration (description, performance, or explanation of a process, illustrated by examples, observable action, specimens, etc)
  • Discussion- Large Group (>12)
  • Discussion-Small Group (Small Group (=12)
  • Independent Learning (Instructor-guided learning activities to be performed by the learner outside of formal educational settings.)
  • Lecture
  • Patient Presentation--Faculty
  • Patient Presentation--Learner
  • Peer Teaching
  • Problem-Based Learning (PBL)
  • Self-Directed Learning (Learners take initiative for their own learning; diagnosing needs; formulating goals; identifying resources; implementing appropriate activities; and evaluating outcomes.)
LEARNING ENVIRONMENT POLICIES:
UCCOM strives to provide medical students with a learning environment that is conducive to their professional growth. All UCCOM and visiting medical students are encouraged to review the Student Handbook.

The Office of Student Affairs and Admissions is available to all UCCOM and visiting medical students to discuss any concerns/questions related to the learning environment. Please call 558-6796 to access faculty/staff that can assist you.
TEACHING:
90% Attending Physician
10% Senior Resident
FEEDBACK:
ASSESSMENT:
  • Case presentations (CPC-style, with clinical case, review of imaging and labs, discussion of pathogy, recent research studies on the diases process).
  • Discussion of cases at sign-out with attending pathologist

ASSESSMENT METHODS:
Clinical Performance Rating/Checklist
Oral Patient Presentation
Participation
FINAL GRADE:
GRADE ASSIGNED BY: Course director

OBJECTIVES

Curricular Resources :







Instructional Methods:
  • Case-Based Instruction/Learning (brain cutting, didactic sessions correlating pathology and Neuology)
  • Conference (CPC -style student presentations)
  • Independent Learning (preparation for sign-out)
  • Laboratory (discussions and review ofpathology procedures)
  • Lecture
  • Mentorship
  • Self-Directed Learning
  • Assessment Methods: Review of neuroanatomy knowledge, basic histopathology skills, general knowledge of Neurology ad Medicine


Knowledge/Skills:

Patient Care (Diagnostic Neuropathology)

  1. Become familiar with the handling and processing of brain biopsies, including frozen sections, intraoperative smear techniques, special fixatives, and EM
  2. Understanding the role of the intraoperative consultation, and the importance of integrating
  3. Clinicoradiologic data.
  4. Utilizing texts and glass slide study sets, in addition to current cases, learn about the different categories of CNS surgical pathology specimens, including infection and neoplasia; be able to diagnose the more common entities.
  5. Participate in brain cutting conference and study common pathologic processes seen post-mortem, e.g. cerebrovascular disease, infection, neurodegenerative disease. Learn from complementary lecture series.

Medical Knowledge

  1. Become familiar with the biologic behavior of common CNS lesions; understand neuropathology grading (WHO) system.
  2. Read text, literature or internet pertaining to cases, with the goal of improving fund of knowledge (diagnostic developments, prognostic features, and ancillary techniques).
  3. Prepare Powerpoint CPC-style presentations
  4. Synthesize information in preparation for inter (or intra) departmental conferences.
  5. Participate in brain cutting conferences.
  6. Complete unkown neuropathology glass slide conference.

Practice Based Learning & Improvement

  1. Learn about diagnostic issues in neuropathology that impact neurosurgical patient management (evidence-based, e.g.the increasing role for molecular studies).
  2. Learn common neuropathology diagnostic pitfalls and how to avoid them.
  3. Prepare and present cases for neuropathology sign-out.
  4. Complete unknown neuropathology glass slide conference.
  5. Communicate effectively with Pathologists/laboratory staff in discussing cases.
  6. Interact with laboratory personnel to discuss specimens, cases and management issues.
  7. Present cases at interdisciplinary conferences (optional).
Main Course Topics :
The rotation (4 weeks only) includes participation in the preparation and interpretation of frozen sections/ intraoperative smear preparations, and histologic diagnosis of neurosurgical specimens; the importance of correlation with clinicoradiologic data is emphasized.  Fourth year students will participate in the work-up of active cases, including special stains, immunohistochemistry, molecular studies, and electronmicroscopy.
Procedures:
  1. Participate in brain cutting conference and study common pathologic processes seen post-mortem, e.g. cerebrovascular disease, infection, neurodegenerative disease.
  2. Learn from complementary lecture series.
Remediation Plan:
 -If needed, remediation will include: required case presentations, attending lectures, participaiton in surgical neuropath sign-out.

SAMPLE WEEK

Monday:
8:00AM 5:00PM Report to NP, 110 LMB
Tuesday:
8:00AM 5:00PM Report to NP, 110 LMB
Wednesday:
8:00AM 11:30AM Report to NP, 110 LMB
11:30AM 1:00PM Neuro-oncology Conference
1:00PM 5:00PM Report to NP, 110 LMB
Thursday:
7:30AM 8:30AM Neuro-muscular Conference
8:30AM 5:00PM Report to NP, 110 LMB
Friday:
8:00AM 5:00PM Report to NP, 110 LMB
SCHEDULE NOTE:

Please arrive on day one at 9:00. You are free to wear scrubs if you like. At some point, on your first day, please touch base with Dr. Kendler, kendlea@ucmail.uc.edu the faculty in charge of your rotation, so that they can go over specific expectations.

If any of you are interested in seeing an autopsy, we always have a resident on that service, and you are welcome to attend any autopsy cases that come in while you are rotating with us.  I recommend you go to at least one.  At some point in your career, you will likely have a family ask about having an autopsy done or to have you interpret an autopsy report for them.  Knowing what actually happens in the morgue will be of value to you when that time happens.

As far as departmental conferences go, I would ask that you attend morning conferences, except your first day (scheduled for 8:00-9:00), SP Case Conference (Thursdays 12:00-1:00) and Unknown Sessions (Fridays 12:00-1:00).  You can consider the other conferences as optional but highly recommended. 

On the Thursday of your last week, you will give a short (15-20 minute) case presentation as part of the SP Case Conference that week.  I would recommend asking either the faculty in charge of your rotation or the attending faculty during your first week if they have an interesting case that you could present so that you have plenty of time to prepare.  If the slides need to pulled, Alex or Vinay can assist you with requesting them.  When you are ready, one of the residents will help you take pictures of the slides to use during your presentation.

Conferences on 4th floor meeting room:

  • Monday
    • Morning Didactic 8:00-9:00
  • Tuesday
    • Morning Didactic 8:00-9:00
    • MIDAS Review 1:00-2:00
    • Consensus Conference 3:00-4:00
  • Wednesday
    • Morning Didactic 8:00-9:00
  • Thursday
    • DLM Rounds 8:00-9:00
    • Micro Plate Rounds 9:30-10:00
    • SP Case Conference 12:00-1:00
    • Consensus Conference 3:00-4:00
  • Friday
    • Morning Didactic 8:00-9:00
    • Unknown Session 12:00-1:00

ATTENDANCE AND ABSENCE POLICY

 

Session Attendance for M4 Students

  • Students may miss no more than two days of planned excused absences on a four week rotation without being required to make-up the work, at the discretion of the clerkship/elective/course director or his/her designee.
  • Non-AI Rotations - Per the Student Duty Hours Policy, an average of one day (24 hours) in every seven must be free of clinical responsibilities (including seminars, clinic, rounds, lectures) averaged over a four week period. These days off are assigned by the clerkship director to best align with the site schedule. Students may request to schedule 1 or more of these 4 days for planned absences that fall under 1 of the categories listed below for excused absences during non-AI rotations, in consultation with the course/elective director, who may or may not approve such planned absences.
  • AI Rotations - Per the Student Duty Hours Policy, an average of one day (24 hours) in every seven must be free of clinical responsibilities (including seminars, clinic, rounds, lectures) averaged over a four week period. These days off are assigned by the course director to best align with the site schedule. Students may request to schedule 1 or 2 of these days for planned absences that fall under 1 of the categories listed below for excused absences during AI rotations, in consultation with the course director, who may or may not approve such planned absences. Students must avoid scheduling Step 2 examinations during an Acting Internship.
  • Excused Absences - The following will be considered excused absences:
    • Diagnostic, preventative, and therapeutic health services (e.g. doctor appointments, physical therapy, counselling, etc).
    • Personal illness, accident or a major catastrophic event
    • Death or serious illness of immediate family members. Immediate family members, as defined by UC, are Grandparents, Brother, Sister, Brother-in law, Sister-in-law, Daughter-in-law, Son-in-law, Father, Mother, Mother-in-law, Father-in-law, Step-sister, Step-brother, Step-mother, Step-father, Spouse or domestic partner, Child, Grandchild, legal Guardian or other person who stands in place of parent (in Loco Parentis)
  • Whenever possible, planned absences should be requested a minimum of six weeks in advance of the start of the clerkship/elective/course in which the absence will occur; this enables the clerkship/course/elective to help plan for educational event scheduling (e.g. a known appointment could be scheduled around with enough notice and the student might not have any required coursework to make up). Absences requested less than 1 week prior to the planned absence may not be considered for a possible excused absence unless extenuating circumstances prevented the student from providing timely notification per the policy. Students should first submit their request for a planned absence to the clerkship/elective/course director using the online MSSF. All planned/excused absences for any reason should be documented on the MSSF.
  • The COM abides by the UC Religious Observance Policy that respects the religious diversity of its students by providing opportunities, where possible, for accommodation in cases where conflicts exist between students’ religious beliefs/practices and educational activities. In clinical settings, such accommodations must honor the primacy of a commitment to patient care and avoid unduly burdening faculty, staff and the general student population involved in the affected educational and/or patient care activity.
  • The following items are explained in detail in the Medical Student Handbook:
    • Excused/unexcused/unplanned absence, religious holidays, jury duty, and make-up work

See Attendance and Absences Policy, Religious Observance Policy, Medical Student Handbook.




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