2024-2025 M3/M4 Course Syllabi
Medical Education
COURSE NUMBER:
28 02 02
TITLE:
CLINICAL TRANSFUSION MEDICINE
This elective at the community's blood center provides an overview of transfusion medicine that includes collection, production and usage of blood components, pretransfusion recipient testing, and transfusion ordering practices. During this elective the student will also receive an overview in the collection and clinical uses for blood products collected by apheresis and the role of HLA antigens in transfusing these products. Exposure to therapeutic apheresis is also available. Solid organ, bone marrow and peripheral blood stem cell transplantation are also described.
PREREQUISITES:
 Please contact Margaret Simon @ margaret.simon@uc.edu with any questions regarding the elective or scheduling for this elective.
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GENERAL INFORMATION

COURSE YEAR:
M4
CREDIT HOURS:
4
CREDIT WEEKS:
2
DOMESTIC VISITING:
NO
INTERNATIONAL VISITING:
NO
GRADED:
Pass/Fail
COURSE QUALIFICATIONS:
STATUS:
Full-Time   
OFFERED AS FULL-TIME AND PART-TIME: NO
ALLOWS OVERLAP: YES
COURSE LENGTH:
2 WKS
DIRECTOR:
David Oh,
ohdd@uc.edu
513-558-1338
Hoxworth Blood Center, 5012
ADMINISTRATIVE SUPPORT PERSON:
Margaret Simon
Simonmp@ucmail.uc.edu
513-558-1335
Hoxworth Blood Center, 5010B
SITE(S):
Hoxworth Blood Center
MAX ENROLL:
1 
ROTATIONS:
Rotation Dates Max
1 05/06/2024 - 05/17/2024 1
2 06/03/2024 - 06/14/2024 1
4 07/29/2024 - 08/09/2024 0
4 08/12/2024 - 08/23/2024 0
5 08/26/2024 - 09/06/2024 0
6 10/07/2024 - 10/18/2024 1
7 11/04/2024 - 11/15/2024 0
8 12/02/2024 - 12/13/2024 0
10 01/13/2025 - 01/24/2025 1

NOTE: If a rotation is offered in both 2 and 4 week slots, the max capacity is limited to the actual spots offered for the 4 weeks. (ie: the 2 week rotations listed share the max of the 4 week rotation)
WORKING HOURS:
9:00 AM - 5:00 PM, Monday - Friday
REPORT 1ST DAY:
Stop at 4th Floor Receptionist, ask for Margaret Simon 558-1335. Most often emails including 2 week schedule and instructions for the first day will be provided, Margaret Simon can be emailed at any time with questions regarding elective and any scheduling issues.

INSTRUCTION

LEARNING ACTIVITIES:
  • Case-Based Instruction/Learning
  • Conference
  • Demonstration (description, performance, or explanation of a process, illustrated by examples, observable action, specimens, etc)
  • Discussion-Small Group (Small Group (=12)
  • Laboratory
  • Lecture
  • Problem-Based Learning (PBL)
LEARNING ENVIRONMENT POLICIES:
UCCOM strives to provide medical students with a learning environment that is conducive to their professional growth. All UCCOM and visiting medical students are encouraged to review the Student Handbook.

The Office of Student Affairs and Admissions is available to all UCCOM and visiting medical students to discuss any concerns/questions related to the learning environment. Please call 558-6796 to access faculty/staff that can assist you.
TEACHING:
15% Attending Physician
15% Other Faculty
60% Other Allied Health Professional(s)
10% Fellow Physician
FEEDBACK:
ASSESSMENT:
 The assessment includes a pass/fail evaluation provided by the Medical School

ASSESSMENT METHODS:
Narrative Assessment
Other: Describe other methods not listed above:
Participation
FINAL GRADE:
GRADE ASSIGNED BY: Course director

OBJECTIVES

Curricular Resources :
Reading and/or Texts

1. McCullough, J. 4th Ed. Transfusion Medicine. Wiley-Blackwell. Chichester, UK. 2016.
2. Technical Manual. American Association of Blood Banks. Bethesda: AABB, current edition.
3. Circular of Information for the use of Human Blood and Blood Components, current edition.
4. Standards for Blood Banks and Transfusion Services. American Association of Blood Banks. Bethesda: AABB, current edition.
5.  Multiple  voice recorded lectures made available during rotation
6. Current Journal Articles from faculty
Instructional Methods:
The student has access to recorded lectures for overview of content, spends time in operational departments for viewing and sometimes performing labwork on pre-tested samples.  Faculty spends time with students during rounds and weekly meetings to go over weekly cases, calls, situations occurring at the blood center. it's a hands on type of rotation, depending on what situations present themselves,
Knowledge/Skills:
Donor Services: 
  • Review Donor Eligibility, questions and health history, mini physical
  • Observe multiple platforms for collection: whole blood, automated apheresis for RBC, PLT, plasma

Components:    
  • Observe manufacturing for WB into RBC, Plasma, Cryo, Platelet components
  • Introduce temperature for manufacturing, storage, transportation
  • Observe  modifications such as Irradiation,
  • Washing, thawing, leukoreduction process, pooling of cryo

Product Management:  
  • Ordering for replacement, explanation of expected turn around time
  • Imports to Hoxworth – time delay

Red Cell Serology:            
  • ABO/Rh, antibody screen and antibody identification, preparation of suitable Antigen negative units, frequencies of antigen negative units, Transfusion practice, Crossmatch methodologies, DAT, intra/extravascular  Hemolysis. Temp storage of  components

Transfusion Service:        
  • Dispense of components for transfusion, inventory challenges, time expectation To re-order components from Hoxworth
  • OR refrigerator and policies for transfusable products
  • Turn around time for Preparation or crossmatch of components
  • Initiation of Massive transfusion protocol
  • Blood Bag Tags

Transplantation Imm:     
  • HLA testing, Crossmatching of donor organs, PCR

Therapeutic Apheresis: 
  • Attend rounds daily, observe procedures, both for collections and infusion, Plasma exchange, Red Cell exchange, be introduced to therapies treated by  apheresis
Main Course Topics :
  • Blood donation
  • Blood safety
  • Blood products
  • Transfusion practices
  • Pretransfusion testing
  • Cellular therapies
  • Therapeutic Apheresis
  • Transplantation immunology
Procedures:
  1. Perform pretransfusion testing:
  2. ABO/Rh typings
  3. Antibody screen/identification
  4. Direct antiglobulin test
  5. Describe apheresis procedures:
  6. Therapeutic
  7. Product collection
  8. Describe Transplant Immunology Laboratory and appropriate testing.
  9. Describe tests required on all allogeneic donors of whole blood or apheresis products.
  10. Describe tests required for autologous donors of whole blood products.
Remediation Plan:
 Repeat the elective.  It would be almost impossible to not pass. As long as the student is present, participates in discussions, presentations, and reviews the recorded lectures, they should pass.  If they are not present, this would be a bigger issue.

SAMPLE WEEK

Monday:
9:00AM 9:30AM Books, reading list, tour of facilities
9:30AM 10:00AM Apheresis Rounds
10:00AM 5:00PM Apheresis
Tuesday:
9:00AM 9:30AM Blood Center Rounds
9:30AM 10:00AM Donor Services: Overview of Donor Qualif
10:00AM 10:30AM Donor Services: Overview Continued
10:30AM 5:00PM Donor Services: Process of Phlebotomy and Care of Donors
Wednesday:
9:00AM 9:30AM Intro to Red Cell Testing
9:30AM 10:00AM Apheresis Rounds
10:00AM 5:00PM Intro to Red Cell Testing
Thursday:
9:00AM 2:00PM UCMC overview of transfusion service
2:00PM 4:00PM donor quality control, testing products
Friday:
9:00AM 9:30AM Cellular Therapy
9:30AM 10:00AM Apheresis Rounds
10:00AM 2:00PM Cell Therapy Lectures - voice recorded
SCHEDULE NOTE:

The schedule shown above is intended to be an example of a typical week. The actual days and times of rotations through the various areas are determined once a student has requested the elective. The student will receive a copy of the schedule on or before the first day of their rotation. Any special circumstances requiring a change of schedule should be discussed with Margaret Simon as soon as possible.


This course is a PASS/FAIL rotation.



ATTENDANCE AND ABSENCE POLICY

 

Session Attendance for M4 Students

  • Students may miss no more than two days of planned excused absences on a four week rotation without being required to make-up the work, at the discretion of the clerkship/elective/course director or his/her designee.
  • Non-AI Rotations - Per the Student Duty Hours Policy, an average of one day (24 hours) in every seven must be free of clinical responsibilities (including seminars, clinic, rounds, lectures) averaged over a four week period. These days off are assigned by the clerkship director to best align with the site schedule. Students may request to schedule 1 or more of these 4 days for planned absences that fall under 1 of the categories listed below for excused absences during non-AI rotations, in consultation with the course/elective director, who may or may not approve such planned absences.
  • AI Rotations - Per the Student Duty Hours Policy, an average of one day (24 hours) in every seven must be free of clinical responsibilities (including seminars, clinic, rounds, lectures) averaged over a four week period. These days off are assigned by the course director to best align with the site schedule. Students may request to schedule 1 or 2 of these days for planned absences that fall under 1 of the categories listed below for excused absences during AI rotations, in consultation with the course director, who may or may not approve such planned absences. Students must avoid scheduling Step 2 examinations during an Acting Internship.
  • Excused Absences - The following will be considered excused absences:
    • Diagnostic, preventative, and therapeutic health services (e.g. doctor appointments, physical therapy, counselling, etc).
    • Personal illness, accident or a major catastrophic event
    • Death or serious illness of immediate family members. Immediate family members, as defined by UC, are Grandparents, Brother, Sister, Brother-in law, Sister-in-law, Daughter-in-law, Son-in-law, Father, Mother, Mother-in-law, Father-in-law, Step-sister, Step-brother, Step-mother, Step-father, Spouse or domestic partner, Child, Grandchild, legal Guardian or other person who stands in place of parent (in Loco Parentis)
  • Whenever possible, planned absences should be requested a minimum of six weeks in advance of the start of the clerkship/elective/course in which the absence will occur; this enables the clerkship/course/elective to help plan for educational event scheduling (e.g. a known appointment could be scheduled around with enough notice and the student might not have any required coursework to make up). Absences requested less than 1 week prior to the planned absence may not be considered for a possible excused absence unless extenuating circumstances prevented the student from providing timely notification per the policy. Students should first submit their request for a planned absence to the clerkship/elective/course director using the online MSSF. All planned/excused absences for any reason should be documented on the MSSF.
  • The COM abides by the UC Religious Observance Policy that respects the religious diversity of its students by providing opportunities, where possible, for accommodation in cases where conflicts exist between students’ religious beliefs/practices and educational activities. In clinical settings, such accommodations must honor the primacy of a commitment to patient care and avoid unduly burdening faculty, staff and the general student population involved in the affected educational and/or patient care activity.
  • The following items are explained in detail in the Medical Student Handbook:
    • Excused/unexcused/unplanned absence, religious holidays, jury duty, and make-up work

See Attendance and Absences Policy, Religious Observance Policy, Medical Student Handbook.




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