2025-2026 M3/M4 Course Syllabi
Pediatrics
COURSE NUMBER:
16 01 32
TITLE:
CLINICAL GENETICS -ICE
The student will participate in all clinical activities of the Division of Human Genetics including dysmorphology and genetic assessments of infants and children, inpatient consults, genetic counseling, prenatal diagnosis, outreach and specialty clinics. **On occasion, the genetics rotation will consider opening spots in those months where it is not classically open for those interested in a career in genetics or those with an urgent educational need. Please contact the course administrator for questions.
PREREQUISITES:
26961373 (PEDIATRICS CORE CLKSP)

The genetics rotation will consider opening spots in those months where it is not filled with third year medical students taking the M3 Specialty Elective/Phase 2 elective.
expand all

GENERAL INFORMATION

COURSE YEAR:
M4
CREDIT HOURS:
8
CREDIT WEEKS:
4
DOMESTIC VISITING:
NO
INTERNATIONAL VISITING:
NO
GRADED:
Pass/Fail
COURSE QUALIFICATIONS:
ICE
STATUS:
Full-Time   
OFFERED AS FULL-TIME AND PART-TIME: NO
ALLOWS OVERLAP: NO
COURSE LENGTH:
2 or 4 wks
DIRECTOR:
Robert Hopkin, MD
rob.hopkin@cchmc.org
513 636-4760
Cincinnati Children's Hospital Medical Center, E5.231
ADMINISTRATIVE SUPPORT PERSON:
Mimi Pence
Mimi.Pence@cchmc.org
513-636-0339
Kasota Building, 7th Floor at CCHMC, BN7.722
SITE(S):
CCHMC - Cincinnati Children's Hospital
MAX ENROLL:
1 
ROTATIONS:
Rotation Dates Max
1 04/21/2025 - 05/02/2025 0
1 04/21/2025 - 05/16/2025 0
1 05/05/2025 - 05/16/2025 0
2 05/19/2025 - 05/30/2025 1
2 05/19/2025 - 06/13/2025 1
2 06/02/2025 - 06/13/2025 1
3 06/16/2025 - 06/27/2025 0
3 06/16/2025 - 07/11/2025 0
3 06/30/2025 - 07/11/2025 0
4 07/14/2025 - 07/25/2025 0
4 07/14/2025 - 08/08/2025 0
4 07/28/2025 - 08/08/2025 0
5 08/11/2025 - 08/22/2025 1
5 08/11/2025 - 09/05/2025 1
6 09/08/2025 - 09/19/2025 1
6 09/08/2025 - 10/03/2025 1
6 09/22/2025 - 10/03/2025 1
7 10/06/2025 - 10/17/2025 0
7 10/06/2025 - 10/31/2025 0
7 10/20/2025 - 10/31/2025 0
8 11/03/2025 - 11/14/2025 1
8 11/03/2025 - 11/28/2025 1
9 12/01/2025 - 12/12/2025 0
9 12/01/2025 - 12/26/2025 0
9 12/15/2025 - 12/26/2025 0
10 12/29/2025 - 01/23/2026 1
10 01/12/2026 - 01/23/2026 1
11 01/26/2026 - 02/06/2026 1
11 01/26/2026 - 02/20/2026 1
12 02/23/2026 - 03/06/2026 0
12 02/23/2026 - 03/20/2026 0
12 03/09/2026 - 03/20/2026 0
13 03/23/2026 - 04/17/2026 0

NOTE: If a rotation is offered in both 2 and 4 week slots, the max capacity is limited to the actual spots offered for the 4 weeks. (ie: the 2 week rotations listed share the max of the 4 week rotation)
WORKING HOURS:
8:00 a.m. - 5:00 p.m. Monday-Friday
REPORT 1ST DAY:
You will receive an email with detailed information prior to the elective from the department.

INSTRUCTION

LEARNING ACTIVITIES:
  • Case-Based Instruction/Learning
  • Clinical Experience - Inpatient
  • Conference
  • Patient Presentation--Faculty
  • Patient Presentation--Learner
  • Research
LEARNING ENVIRONMENT POLICIES:
UCCOM strives to provide medical students with a learning environment that is conducive to their professional growth. All UCCOM and visiting medical students are encouraged to review the Student Handbook.

The Office of Student Affairs and Admissions is available to all UCCOM and visiting medical students to discuss any concerns/questions related to the learning environment. Please call 558-6796 to access faculty/staff that can assist you.
TEACHING:
70% Attending Physician
15% Senior Resident
5% Research Faculty
5% Other Faculty
5% Other Allied Health Professional(s)
FEEDBACK:
ASSESSMENT:

ASSESSMENT METHODS:
Clinical Performance Rating/Checklist
Participation
FINAL GRADE:
GRADE ASSIGNED BY: Course director

OBJECTIVES

Curricular Resources :
Aase - Approach to Dysmorphology
  Jones - Smith's Recognizable Patterns of Human Malformations
  Scriver - Metabolic and Molecular Basis of Inherited Disease

Gorlin - Syndromes of the Head and Neck

  (computer programs, activities, videos, slides, etc.)
  GeneClinics  http://www.geneclinics.org

London Dysmorphology Database

POSSUM database

OMIM (on-line database of genetic conditions that is free and available to anyone with a computer)
Knowledge/Skills:
CLINICAL GENETICS

1.   Obtain a clear and complete medical history focusing on the relevant genetic issues.
2.   Obtain and document, using standard symbols, a 4-generation pedigree.
3.   Explain indications for a genetic evaluation.
4.   Perform a physical examination identifying dysmorphic features and showing an understanding of their relevance to the patient's presenting complaint.
5.   Present the history and physical findings to the attending and establish an appropriate differential diagnosis and diagnostic/follow-up plan.
6.   Understand the laboratory studies used in evaluation of patients with known or suspected genetic disorders including appropriate use of chromosome, metabolic, and DNA diagnostic studies.
7.   Understand follow-up care for patients and families with known genetic disorders.
8.   Develop knowledge of texts, computer databases, and journal articles relevant to the practice of medical genetics.
9.   Be able to understand the need for genetic counseling of patients and/or families regarding the implications of the diagnosis of a genetic disease in the patient (prognosis), risk to other family members, and recurrence risks for future children.

  

PRENATAL GENETICS AND GENETIC COUNSELING

1.   Obtain a complete and accurate medical history, obstetrical history, and family history, and identify important factors which could impact upon the current pregnancy.
2.   Have a working knowledge of all significant issues in prenatal genetics, including:  risks of chromosomal abnormalities, specific malformations, and patterns of malformation in the fetus and their implications regarding the possibility of the presence of genetic syndromes and their prognosis.
3.   Make appropriate use of computer databases, articles, and consultants in arriving at diagnoses and recommendations.
4.   Make appropriate recommendations for further evaluation or a course of medical follow-up correctly identifying the correct risk factors.
5.   Understand the role of a support network for families where a fetal malformation is identified and be able to identify appropriate support groups or other resources for families.
6.   Identify when to consult a medical geneticist and when genetic counseling is indicated.
Main Course Topics :
  • Modes of inheritance
  • Causes of birth defects
  • Genetic counseling
  • Adult onset genetic disorders
  • Management of genetic disorders
Procedures:

Remediation Plan:
 The Director's Discretion.

SAMPLE WEEK

SCHEDULE NOTE:

 STRUCTURE OF THE CLINICAL GENETIC ELECTIVE

Ths course will spend approximately two inpatients with consults and two weeks outpatient with clinics. 

 A. Clinical genetics conferences.  There is a Clinical genetics conference held each Monday from 1:00 - 2:00 P.M.    Students are expected to attend CHMC Grand Rounds on Tuesday from 8:00 A.M. to 9:00 A.M.  Also, Emerging Topics in Medical Genetics on Thursday from 12:00 to 1:00 P.M. is to be attended.

 B. Genetics Clinic patients are seen during out-patient clinic hours throughout the week.  Metabolic Disease Clinics are held on Wednesday afternoon beginning at 1:00 P.M.  All individuals taking the elective should make themselves available to observe patient evaluations with as many of the clinical staff as possible.  In addition, those taking the elective will see patients for evaluation and management with appropriate supervision from an attending clinical genetics staff member.

 C. Prenatal counseling.  There will be opportunities to observe and participate in prenatal counseling sessions with the genetic counselors and/or a clinical genetics physician when appropriate.
 D. Consultations.  Those taking the elective are encouraged to participate in performing inpatient genetic consultations.  These will be fully supervised by an attending clinical genetics physician with genetic counselor participation as indicated.  Students will accompany the clinical geneticist to other hospitals when necessary.

 E. Specialty Clinics.  The Clinical Genetics staff participate in numerous genetics specialty clinics.  Depending on the students rotation time, any of the following clinics will be included in the experience of the student:  Neurofibromatosis Clinic, Craniofacial Anomaly Team, Tuberous Sclerosis Clinic, Marfan Syndrome Clinic, Connective Tissue Clinic, Hereditary Cancer Clinic, Adult Genetics Clinic, Lysosomal Storage Disease Program.

F. Outreach and Satellite Clinics.  Genetics services are provided in outreach settings for patients and families who live a distance from Cincinnati.  Sites include Adams, Brown and Highland Counties.


ATTENDANCE AND ABSENCE POLICY

 

Session Attendance for M4 Students

  • Students may miss no more than two days of planned excused absences on a four week rotation without being required to make-up the work, at the discretion of the clerkship/elective/course director or his/her designee.
  • Non-AI Rotations - Per the Student Duty Hours Policy, an average of one day (24 hours) in every seven must be free of clinical responsibilities (including seminars, clinic, rounds, lectures) averaged over a four week period. These days off are assigned by the clerkship director to best align with the site schedule. Students may request to schedule 1 or more of these 4 days for planned absences that fall under 1 of the categories listed below for excused absences during non-AI rotations, in consultation with the course/elective director, who may or may not approve such planned absences.
  • AI Rotations - Per the Student Duty Hours Policy, an average of one day (24 hours) in every seven must be free of clinical responsibilities (including seminars, clinic, rounds, lectures) averaged over a four week period. These days off are assigned by the course director to best align with the site schedule. Students may request to schedule 1 or 2 of these days for planned absences that fall under 1 of the categories listed below for excused absences during AI rotations, in consultation with the course director, who may or may not approve such planned absences. Students must avoid scheduling Step 2 examinations during an Acting Internship.
  • Excused Absences - The following will be considered excused absences:
    • Diagnostic, preventative, and therapeutic health services (e.g. doctor appointments, physical therapy, counselling, etc).
    • Personal illness, accident or a major catastrophic event
    • Death or serious illness of immediate family members. Immediate family members, as defined by UC, are Grandparents, Brother, Sister, Brother-in law, Sister-in-law, Daughter-in-law, Son-in-law, Father, Mother, Mother-in-law, Father-in-law, Step-sister, Step-brother, Step-mother, Step-father, Spouse or domestic partner, Child, Grandchild, legal Guardian or other person who stands in place of parent (in Loco Parentis)
  • Whenever possible, planned absences should be requested a minimum of six weeks in advance of the start of the clerkship/elective/course in which the absence will occur; this enables the clerkship/course/elective to help plan for educational event scheduling (e.g. a known appointment could be scheduled around with enough notice and the student might not have any required coursework to make up). Absences requested less than 1 week prior to the planned absence may not be considered for a possible excused absence unless extenuating circumstances prevented the student from providing timely notification per the policy. Students should first submit their request for a planned absence to the clerkship/elective/course director using the online MSSF. All planned/excused absences for any reason should be documented on the MSSF.
  • The COM abides by the UC Religious Observance Policy that respects the religious diversity of its students by providing opportunities, where possible, for accommodation in cases where conflicts exist between students’ religious beliefs/practices and educational activities. In clinical settings, such accommodations must honor the primacy of a commitment to patient care and avoid unduly burdening faculty, staff and the general student population involved in the affected educational and/or patient care activity.
  • The following items are explained in detail in the Medical Student Handbook:
    • Excused/unexcused/unplanned absence, religious holidays, jury duty, and make-up work

See Attendance and Absences Policy, Religious Observance Policy, Medical Student Handbook.




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