2026-2027 M3/M4 Course Syllabi

Ophthalmology
COURSE NUMBER:
12 01 36
TITLE:
OPHTHALMIC RESEARCH
The student will participate in on-going basic science research projects in ophthalmic laboratories. In consultation with the elective director, the student will develop a research project in the area of ocular molecular genetics using transgenic mice models to investigate eye development and diseases, therapeutic strategies in treating congenital and acquired eye diseases using techniques of gene therapy and stem cell transplantation.
PREREQUISITES:
Meet with Dr. Liu prior to enrollment.
expand all

GENERAL INFORMATION

COURSE YEAR:
M4
CREDIT HOURS:
16
CREDIT WEEKS:
4
DOMESTIC VISITING:
NO
INTERNATIONAL VISITING:
NO
GRADED:
Honors/High Pass/Pass/Fail
COURSE QUALIFICATIONS:
STATUS:
Full-Time   
OFFERED AS FULL-TIME AND PART-TIME: NO
ALLOWS OVERLAP: YES
COURSE LENGTH:
4
DIRECTOR:
Chia-Yang Liu, PHD
LIUCG@EMAIL.UC.EDU
513-558-7072
MSB , 5007
ADMINISTRATIVE SUPPORT PERSON:
Michele Wyan
michele.wyan@uc.edu
(513) 558-0815
MSB, 5110
SITE(S):
CARE Building
MAX ENROLL:
1 
ROTATIONS:
Rotation Dates Max
1 04/06/2026 - 05/01/2026 0
2 05/04/2026 - 05/29/2026 1
3 06/01/2026 - 06/26/2026 0
4 06/29/2026 - 07/24/2026 0
5 07/27/2026 - 08/21/2026 0
6 08/24/2026 - 09/18/2026 1
7 09/21/2026 - 10/16/2026 1
8 10/19/2026 - 11/13/2026 1
9 11/16/2026 - 12/11/2026 0
10 12/14/2026 - 01/08/2027 0
11 01/11/2027 - 02/05/2027 1
12 02/08/2027 - 03/05/2027 1
13 03/08/2027 - 04/02/2027 1
14 04/05/2027 - 04/30/2027 0

NOTE: If a rotation is offered in both 2 and 4 week slots, the max capacity is limited to the actual spots offered for the 4 weeks. (ie: the 2 week rotations listed share the max of the 4 week rotation)
PT Extended Electives will span the entire year, not just 4 weeks
WORKING HOURS:
8:30 - 5:00 p.m.
REPORT 1ST DAY:
You will receive an email with detailed information prior to the elective start date.

INSTRUCTION

LEARNING ACTIVITIES:
  • Conference
  • Demonstration (description, performance, or explanation of a process, illustrated by examples, observable action, specimens, etc)
  • Laboratory
  • Research
 
In this course, we may cover complex health issues that often intersect with personal beliefs, societal debate, and evolving science. You will likely encounter information or perspectives that differ from your own. As physicians-in-training, your responsibility is to listen with curiosity, engage with evidence, and communicate respectfully—just as we do in patient care. Syllabi and course materials will be grounded in evidence-based medicine, scientific principles and reflect areas of ongoing scientific inquiry. In courses addressing policy, ethics, or societal issues, materials will be structured to promote evidence-based learning while transparently acknowledging where evidence is evolving or there are multiple viewpoints that may impact patient care.
LEARNING ENVIRONMENT POLICIES:
UCCOM strives to provide medical students with a learning environment that is conducive to their professional growth. All UCCOM and visiting medical students are encouraged to review the Student Handbook.

The Office of Student Affairs and Admissions is available to all UCCOM and visiting medical students to discuss any concerns/questions related to the learning environment. Please call 558-6796 to access faculty/staff that can assist you.
TEACHING:
50% Research Fellow
50% elective director
FEEDBACK:
ASSESSMENT:

ASSESSMENT METHODS:
Participation
Practical (Lab)
Research or Project Assessment
FINAL GRADE:
GRADE ASSIGNED BY: Course director

OBJECTIVES

Curricular Resources :
Readings will be assigned according to the research project.
Knowledge/Skills:
1. Learn basic laboratory skills, e.g., column chromatography, tissue culture, cloning, gene therapy strategy.
2. Acquire proficiency in methods to study ocular disorders, e.g., wound-healing in mouse corneas, use of monoclinal antibodies to localize components of extracellular matrix molecular biology, signaling transduction.
3. Regulation of gene expression during Embryonic Development using transgenic and knockout mice.
4. Surgery skills
5. Produce data which will be used for publication by combining the results obtained by other investigators in the laboratories.
Main Course Topics :
  • Molecular biology
  • Genetics
  • Protein chemistry
  • Wound healing
  • Ocular pathology
  • Development
Procedures:
  1. Perform basic laboratory techniques: pipetting, measure pH
  2. Prepare solutions
  3. Demonstrate simple surgical skill on ocular tissues
  4. Molecular cloning
  5. Perform immunohistochemistry
Remediation Plan:
 The student will meet with the course director and discuss how to make up missed assignments.

SAMPLE WEEK

Inpatient Weeks:
Outpatient Weeks:
SCHEDULE NOTE:

STUDENTS WILL DISCUSS POENTIAL RESEARCH INTERESTS UNDERWAY IN THE OPHTHALMIC RESEARCH LABORATORIES.


ATTENDANCE AND ABSENCE POLICY

 

Session Attendance for M4 Students

  • Students may miss no more than two days of planned excused absences on a four week rotation without being required to make-up the work, at the discretion of the clerkship/elective/course director or his/her designee.
  • Non-AI Rotations - Per the Student Duty Hours Policy, an average of one day (24 hours) in every seven must be free of clinical responsibilities (including seminars, clinic, rounds, lectures) averaged over a four week period. These days off are assigned by the clerkship director to best align with the site schedule. Students may request to schedule 1 or more of these 4 days for planned absences that fall under 1 of the categories listed below for excused absences during non-AI rotations, in consultation with the course/elective director, who may or may not approve such planned absences.
  • AI Rotations - Per the Student Duty Hours Policy, an average of one day (24 hours) in every seven must be free of clinical responsibilities (including seminars, clinic, rounds, lectures) averaged over a four week period. These days off are assigned by the course director to best align with the site schedule. Students may request to schedule 1 or 2 of these days for planned absences that fall under 1 of the categories listed below for excused absences during AI rotations, in consultation with the course director, who may or may not approve such planned absences. Students must avoid scheduling Step 2 examinations during an Acting Internship.
  • Excused Absences - The following will be considered excused absences:
    • Diagnostic, preventative, and therapeutic health services (e.g. doctor appointments, physical therapy, counselling, etc).
    • Personal illness, accident or a major catastrophic event
    • Death or serious illness of immediate family members. Immediate family members, as defined by UC, are Grandparents, Brother, Sister, Brother-in law, Sister-in-law, Daughter-in-law, Son-in-law, Father, Mother, Mother-in-law, Father-in-law, Step-sister, Step-brother, Step-mother, Step-father, Spouse or domestic partner, Child, Grandchild, legal Guardian or other person who stands in place of parent (in Loco Parentis)
  • Whenever possible, planned absences should be requested a minimum of six weeks in advance of the start of the clerkship/elective/course in which the absence will occur; this enables the clerkship/course/elective to help plan for educational event scheduling (e.g. a known appointment could be scheduled around with enough notice and the student might not have any required coursework to make up). Absences requested less than 1 week prior to the planned absence may not be considered for a possible excused absence unless extenuating circumstances prevented the student from providing timely notification per the policy. Students should first submit their request for a planned absence to the clerkship/elective/course director using the online MSSF. All planned/excused absences for any reason should be documented on the MSSF.
  • The COM abides by the UC Religious Observance Policy that respects the religious diversity of its students by providing opportunities, where possible, for accommodation in cases where conflicts exist between students’ religious beliefs/practices and educational activities. In clinical settings, such accommodations must honor the primacy of a commitment to patient care and avoid unduly burdening faculty, staff and the general student population involved in the affected educational and/or patient care activity.
  • The following items are explained in detail in the Medical Student Handbook:
    • Excused/unexcused/unplanned absence, religious holidays, jury duty, and make-up work

See Attendance and Absences Policy, Religious Observance Policy, Medical Student Handbook.




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